The management of NMS should be based on a hierarchy of symptom severity. Antipsychotics should be used conservatively with gradual titration of doses. All patients with psychosis should be monitored daily for dehydration and elevated temperature, have vital signs checked and agitation should be watched for.
dehydration, agitation and exhaustion), early recognition of suspected cases and prompt discontinuation of the offending agent. This includes reducing risk factors (e.g. The most important aspect of treatment is prevention. The presentation and course of NMS can be quite variable ranging from a stormy and potentially fatal course to a relatively benign and self-limiting course. The diagnosis of NMS presents a challenge because several medical conditions generate similar symptoms. Increased awareness and early recognition will lead to prompt management. Neuroleptic malignant syndrome (NMS) is a rare but potentially lethal form of drug-induced hyperthermia characterised by mental status changes, muscle rigidity, hyperthermia and autonomic dysfunction.
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